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TNF-α acts on its receptors TNF21 and TNFR1/2 and triggers the activation of various signaling pathways of renal fibrosis, including TGF-β, mitogen-activated protein kinase (MAPK), NF-κB and NADPH oxidase (129–132)

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Relative efficacy of three medicinal plant extracts in the alteration of thyroid hormone concentrations in male mice