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Há ainda uma nuance de segurança que os estudos de absorção levantam de forma incontornável: o que aumenta a penetração de ativos benéficos aumenta também a de contaminantes

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AuNPs-d-PLL.siRNA 25 nM witnessed a decrease in zeta potential from +32 ± 1.3 mV to -21.13 ± 0.5 mV, followed by PEGylated forms, AuNPs-d-PLL-PEG.siRNA 25 nM, with a charge of -14.13 ± 4.87 mV, and finally the surface charge decreased from +30.2 ± 0.9 mV to reach -11.41 ± 3.78 mV for AuNPs-d-PLL-FA.siRNA 25 nM (Table 2)