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3 Regulatory effects on stroma cells in TME It’s commonly known that tumorigenesis is usually accompanied by the formation of the tumor bed as well as the remodeling of the surrounding extracellular matrix (ECM), in which tumor stromal cells play a pivotal role, thus forming a suitable TME for tumor cell survival, so targeting relevant stromal cells is critical to cancer treatment

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Thigh: Upper outer portion of the thigh, between the front and side of the leg