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As shown in Figure 7 , in mock- and GSTP1 -transfected HepG2 cells dose- and time- dependent up-regulations of CHOP-GFP signal were detected following treatment with AQ-QI or DEAQ-QI

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In vivo , lactylation at H4K12la promotes expression of Hif1α and enhances endometrial glycolysis, and in turn forms an H4K12la-Hif1α-glycolysis feedback loop to drive decidualization (49)