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Mechanistically, FSP1 stability depends on its cofactor flavin adenine dinucleotide (FAD), which is synthesized from riboflavin by riboflavin kinase (RFK) and FAD synthase (FLAD1) [21]

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With regard to recognition of conformational epitopes, the binding domain recognizes a three- dimensional structure of the antigen, preferably a peptide or protein or fragment thereof (in the context of the present invention, the antigenic structure for one of the binding domains is comprised within the target cell surface antigen protein)