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Mendes de Almeida Junior A, Ferreira AS, Camacho SAS, Gontijo Moreira L, de Toledo KA, Oliveira Jr ON, et al

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Interestingly, AUD subjects were found to have increased methylation of the C variant of 3′-UTR SNP rs2235749 (a PDYN CpG SNP known to be associated with AUD) in the dlPFC compared to control subjects, and this methylation was positively correlated with dynorphin expression