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Divergent behaviour of oxidative stress markers 8-hydroxydeoxyguanosine (8-OHdG) and 4-hydroxy-2-nonenal (HNE) in breast carcinogenesis

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Liver shows the highest absorption, with biliary concentration of silibinin being up to 100-fold as compared to plasma levels, since active concentrating mechanisms in the liver magnify circulating levels in hepatocytes (Sun Y