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Figure 4 Discussion Structural analyses of the ghrelin receptor, enabled by advancements in structural biology techniques such as X-ray crystallography and cryo-EM, have provided detailed insights into the molecular mechanisms underlying the recognition of active ghrelin by its receptor

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Several studies have shown that cyclophosphamide markedly elevated expression of the pro-apoptotic proteins: p53, Bax and caspase3 enzyme besides the markedly reduced expression of the anti-apoptotic protein BCL-2 [23, 25, 62, 63]