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100 - Office Hours: PWC26 Virtual Summit Part 2 Office Hours PWC26 Virtual Summit Part 2 – Episode 100 Office Hours PWC26 Virtual Summit Part 2 – Episode 100 Evaluating terrain of the patient (1:43) SS31 peptide in practice (8:50) Phenotyping the right patient for GLP-1 therapy (11:18) William Seeds, MD Aug 6, 2026 A Lipid at the Root of Mitochondrial Aging: Phosphatidylcholine, Methylation, and a Malleable Therapeutic Window Mitochondrial dysfunction is one of the most firmly established hallmarks of aging, but the field has spent far more energy describing genetic causes of mitochondrial failure—mtDNA mutation, defective OXPHOS, impaired unfolded protein response—than the “natural” drivers that erode mitochondria during ordinary aging

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