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The aim of our study was to retrospectively evaluate, under real life conditions, the on-treatment survival of patients with advanced HCC (BCLC-C stage), either initially presenting in the advanced stage (iBCLC-C) or migrating from BCLC-A to BCLC-C stage (mBCLC-C) within 2 years after curative LR or RFA, treated either with atezolizumab-bevacizumab (ATZ/BEV) combination or with TKIs sequentially (sorafenib as 1 st line and cabozantinib as 2 nd line treatment)

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In this review, we provide an overview of autophagy and ferroptosis and a comprehensive review of the molecular mechanisms of autophagy-dependent ferroptosis and its regulation