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Activated microglia and reactive astrocytes release large amounts of glutamate (Takeuchi et al., 2006

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In China, the prevalence among children aged 0–6 years is 1.8% (Zhou et al., 2020), and 2020 data from the United States reveal that 2.76% of 8-year-olds have ASD, representing an increase of 0.46% compared to 2018 (Maenner et al., 2021