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TRANSCEND trial: Approved treatments are lacking for acquired hypothalamic obesity. New research findings on the efficacy and safety of setmelanotide, a melanocortin-4 receptor agonist, are summarized in a Quick Take video: https://nej.md/4eVGFg9

Hostynek JJ, Maibach HI

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For survival experiments, SCID mice were monitored daily for the development of clinical signs of disease and examined in case any abnormality of behavior was observed

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