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In EndMT, ECs lose endothelial markers (e.g., VE-cadherin, CD31, so known as platelet endothelial cell adhesion molecule-1, PECAM-1) and acquire mesenchymal traits (e.g., alpha-smooth muscle actin, vimentin), driven by transcription factors such as snail family transcriptional repressor and zinc finger e-box–binding homeobox 1

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[DOI] [PMC free article] [PubMed] [Google Scholar] 148.Chen J.Y., Tran C., Hwang L., Deng G., Jung M.E., Faull K.F., Levine M.S., Cepeda C