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In mouse models of inflammatory bowel disease, downregulation of NF-κB signaling and reduction of proinflammatory cytokines have been associated with reduced local mucosal inflammation (Kannengiesser et al

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Keywords: canine, cobalamin, chronic enteropathy, treatment, vitamin D Abstract Chronic enteropathy (CE) or chronic inflammatory enteropathy is a group of diseases with multiple and different etiologies characterized by chronic gastrointestinal signs such as vomiting, diarrhea, anorexia, weight loss for more than 3 weeks, and inflammatory cell infiltration, such as lymphoplasmacytic cells in the intestinal mucosal lamina propria