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Your tolerance just means that you don’t feel as drunk but people on average metabolize alcohol the same way and it is that rate which your body metabolizes alcohol that determines your BAC content

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NNMT is a cytoplasmic enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide (1-MNA) and S-adenosylhomocysteine (SAH)