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Supplementation with Akkermansia helps increase the expression of mucin, promotes the proliferation and differentiation of goblet cells in the intestinal epithelium, and effectively protects the structure and function of the intestinal barrier

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It affects an enzyme called NNMT, which acts like a metabolic leak—draining away essential components: 👉 NAD (crucial for energy production) 👉 SAM (the universal methyl donor) This is significant, especially since NNMT is upregulated in conditions such as obesity, diabetes, Alzheimer’s, Parkinson’s, and aging